Sahajanand Medical Technologies Limited Bags the Prestigious National Technology Awards 2022 Conferred by the Government of India for Supraflex Cruz www.businesswireindia.com May 17, 2022, 12:01 p.m.
The awards were given by the Technology Development Board (TDB), a statutory body of Government of India functioning under Department of Science of Technology for the year 2021-22. The winners were selected from a total 390 applications after thorough examination by eminent technologists and a stringent two-tier evaluation process. The winners have been selected under the categories --Indigenous Technologies, MSME, Startups, and Women Scientists in Translational Research and Women Entrepreneurs. Dr S. Chandrasekhar, Secretary, DST and Shri Rajesh Kumar Pathak, IP&TAFS, Secretary TDB were Guests of Honours.
Next-generation DES gains FDA approval www.healio.com May 16, 2022, 8:55 a.m.
Medtronic announced it received FDA approval for its next generation drug-eluting stent. The new DES (Onyx Frontier) utilizes the same stent platform as its previous DES (Resolute Onyx), with a delivery system designed to improve deliverability and increase acute performance, according to a press release issued by the company.
Treatment of coronary bifurcation lesions, part I: implanting the first stent in the provisional pathway. The 16th expert consensus document of the European Bifurcation Club eurointervention.pcronline.com May 16, 2022, 8:55 a.m.
Stepwise layered provisional stenting (PS) is the most commonly used strategy to treat coronary bifurcation lesions (CBL). The term “stepwise layered” emphasises the versatility of this approach that allows the adjustment of the procedure plan according to the CBL complexity, starting with stent implantation in one branch and implantation of a second stent in the other branch only when required. A series of refinements have been implemented over the years to facilitate the achievement of predictable procedural results using this approach. However, despite its simplicity and versatility, operators using this technique require full knowledge of the pitfalls of each procedural step.
Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation www.thelancet.com May 16, 2022, 8:54 a.m.
Intimal hyperplasia (IH) remains a major limitation in the long-term success of any type of revascularisation. IH is due to vascular smooth muscle cell (VSMC) dedifferentiation, proliferation and migration. The gasotransmitter Hydrogen Sulfide (H2S), mainly produced in blood vessels by the enzyme cystathionine- γ-lyase (CSE), inhibits IH in pre-clinical models. However, there is currently no H2S donor available to treat patients. Here we used sodium thiosulfate (STS), a clinically-approved source of sulfur, to limit IH.
Drug-Coated Balloons for Dysfunctional Dialysis Arteriovenous Fistulas www.nejm.org May 16, 2022, 8:53 a.m.
Drug-coated balloon angioplasty was superior to standard angioplasty for the treatment of stenotic lesions in dysfunctional hemodialysis arteriovenous fistulas during the 6 months after the procedure and was noninferior with respect to access circuit–related serious adverse events within 30 days.
ISABELLA: New sirolimus data provide encouragement despite “potentially disappointing” efficacy results vascularnews.com May 16, 2022, 8:52 a.m.
The results of a small-scale pilot study from Asia have indicated “potentially disappointing” results with a novel drug-eluting balloon in treating dysfunctional arteriovenous access for dialysis. These findings were delivered by Tjun Tang (Singapore General Hospital, Singapore)—who also highlighted “excellent” technical and clinical success rates and positive safety outcomes—via a Podium 1st presentation at the 2022 Charing Cross (CX) International Symposium (26–28 April, London, UK).
Treatment of coronary bifurcation lesions, part II: implanting two stents. The 16th expert consensus document of the European Bifurcation Club eurointervention.pcronline.com May 16, 2022, 8:51 a.m.
The European Bifurcation Club (EBC) supports a continuous review of the field of coronary artery bifurcation interventions and aims to facilitate a scientific discussion and an exchange of ideas on the management of bifurcation disease. The recent focus of meetings and consensus statements has been on the technical issues in bifurcation stenting, recognising that the final result of a bifurcation procedure and the long-term outcome for our patients are strongly influenced by factors, including preprocedural strategy, stenting technique selection, performance of optimal procedural steps, the ability to identify and correct complications and finally, and most important, the overall performance of the operator.
A GUIDE TO COMBINE DCB & DES IN HYBRID PCI cm.pcronline.com May 15, 2022, 5:47 p.m.
Learn about how to combine usage of DES with DCB with the goal to limit stent length and allowing the potential for vessel remodeling following usage of DCB Receive an in-depth insight into the latest clinical data on drug-coated balloon usage in ISR, de-novo and bifurcation indications Learn more about your options to use drug-coated balloons in ACS patients
New cell therapy approach to regenerate cardiac tissue following a heart attack news.ki.se May 15, 2022, 5:29 p.m.
Researchers at Karolinska Institutet, Germany’s Technical University of Munich (TUM) and AstraZeneca, among others, have identified a unique therapeutic approach with the potential to restore heart function following a heart attack. The new findings rely on so-called human ventricular progenitor (HVP) cells to promote novel heart tissue and reduce scarring after injury. This pre-clinical study is published in the journal Nature Cell Biology.
Chip startups using light instead of wires gaining speed and investments www.reuters.com May 13, 2022, 2:02 p.m.
Computers using light rather than electric currents for processing, only years ago seen as research projects, are gaining traction and startups that have solved the engineering challenge of using photons in chips are getting big funding.
Converting Concepts into Reality www.conceptmedical.com May 13, 2022, 10:42 a.m.
With a mission “Converting concepts into reality” Concept Medical delivers medical devices that address unmet clinical needs in cardiovascular.
Selective intracoronary hypothermia in patients with ST-elevation myocardial infarction. Rationale and design of the EURO-ICE trial eurointervention.pcronline.com May 9, 2022, 10:28 a.m.
In animal models of acute myocardial infarction, it has been demonstrated that hypothermia decreases IS3. In contrast, human studies applying systemic cooling methods have not yet been able to confirm this protective effect. Recently, we developed a new method to provide selective intracoronary hypothermia during PPCI4. Th
Clinical outcomes with unselected use of an ultrathin-strut sirolimus-eluting stent: a report from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) eurointervention.pcronline.com May 9, 2022, 9:09 a.m.
The aim of this study was to assess the real-world clinical performance of a sirolimus-eluting ultrathin-strut drug-eluting stent (DES) (Orsiro) in a large nationwide cohort of patients undergoing percutaneous coronary intervention (PCI).
Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation www.thelancet.com May 9, 2022, 9:09 a.m.
Intimal hyperplasia (IH) remains a major limitation in the long-term success of any type of revascularisation. IH is due to vascular smooth muscle cell (VSMC) dedifferentiation, proliferation and migration. The gasotransmitter Hydrogen Sulfide (H2S), mainly produced in blood vessels by the enzyme cystathionine- γ-lyase (CSE), inhibits IH in pre-clinical models. However, there is currently no H2S donor available to treat patients. Here we used sodium thiosulfate (STS), a clinically-approved source of sulfur, to limit IH.
Optical coherence tomography in coronary atherosclerosis assessment and intervention www.nature.com May 5, 2022, 7:01 p.m.
Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in the management of patients with acute coronary syndromes. Detection by OCT of healed coronary plaque has been important in our understanding of the mechanisms involved in plaque destabilization and healing with the rapid progression of atherosclerosis.
OCTOPUS – optical coherence tomography plaque and stent analysis software deepai.org May 5, 2022, 7 p.m.
Compared with other imaging modalities, intravascular optical coherence tomography (IVOCT) has significant advantages for guiding percutaneous coronary interventions. To aid IVOCT research studies, we developed the Optical Coherence TOmography PlaqUe and Stent (OCTOPUS) analysis software. To automate image analysis results, the software includes several important algorithmic steps: pre-processing, deep learning plaque segmentation, machine learning identification of stent struts, and registration of pullbacks. Interactive visualization and manual editing of segmentations were included in the software.
Angiographie coronarienne www.advehealth.com May 5, 2022, 6:55 p.m.
Une angiographie est une procédure qui est faite pour effectuer l'angiographie. En d'autres termes, une angiographie est une procédure et une angiographie est un résultat. Il n'y a pas de différence entre l'angiographie et l'angiogramme, les deux sont utilisés comme synonymes.
Is China Still A Good Opportunity For Device Manufacturers? www.medtechintelligence.com May 5, 2022, 6:54 p.m.
The best way to succeed in China is to focus on selling unique products there; unique products that are needed, where the reimbursements are still relatively good, and VBP will not reduce prices, yet can still yield large sales. Western brands are still perceived as higher quality than locally made products, and are popular with Chinese patients as long as the pricing is reasonable. Other strategies to be successful in China include licensing or selling your technology since there is more Chinese capital available these days. Another improved factor, although still not great, includes better intellectual property protection in China. Some Western companies are also making more of their products in China, which can help the company to be closer to their customers, in some cases make registration easier, and may reduce manufacturing costs.
Crosstalk of Magnesium and Serum Lipids in Dyslipidemia and Associated Disorders: A Systematic Review www.mdpi.com May 5, 2022, 6:47 p.m.
Dyslipidemia is a significant threat to public health worldwide and the identification of its pathogenic mechanisms, as well as novel lipid-lowering agents, are warranted. Magnesium (Mg) is a key element to human health and its deficiency has been linked to the development of lipid abnormalities and related disorders, such as the metabolic syndrome, type 2 diabetes mellitus, or cardiovascular disease. In this review, we explored the associations of Mg (dietary intake, Mg concentrations in the body) and the lipid profile, as well as the impact of Mg supplementation on serum lipids.
New Revascularization Guidelines: Key Points and Controversies www.medscape.com May 5, 2022, 6:46 p.m.
We really try to focus on the newer evidence in the past 10 years. Obviously, for certain situations, you need to bring in the old evidence so you can balance the two. We generally say 10 years, but the truth of the matter is we really went back for just about everything to many years ago because some of the data — for example, the data on left main disease — stemmed from trials from 40 years ago without newer data, so we had to take stuff beyond 10 years.